The first antibiotic penicillin was discovered by Alexander Fleming in 1928 (Fleming, 1929), and more than 100 compounds have been found since, but no new class has been found since 1987 (Ling et al,...
Generally, in order for a drug to exert an effect on the body, the drug must bind to a receptor. The word ‘receptor’ can be used to describe all target molecules for drug binding, and it is used in...
The majority of drugs do not exert their effects in the compartment into which they are delivered, e.g. the gastrointestinal tract for drugs given orally or the plasma for drugs given intravenously....