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Patient care report

Diagnosis of haemophilia A in a Miniature Longhaired Dachshund

02 October 2017
Clinical
11 mins read
02 October 2017
Volume 8 · Issue 8
Figure 1. The patient at initial presentation.
Figure 1. The patient at initial presentation.

Abstract

This case report presents a 6-month-old, male, Miniature Longhaired Dachshund diagnosed with haemophilia A. The clinical procedures, as well as nursing interventions, leading to the diagnosis are presented. Treatment and management of haemophilia A is also described.

Haemophilia A is a severe, inherited, bleeding disorder that affects several mammals including dogs (Aslanian et al, 2014). It has an estimated incidence in human populations of 1–2 cases per 10 000 male births (Brooks et al, 2005). However there are fewer reported studies in veterinary medicine and the prevalence of dogs with haemophilia A is unknown. Similar to the human condition, it is associated with high morbidity and mortality (Callan et al, 2016). It is caused by a deficiency of clotting factor eight, represented by Roman numeral VIII or (FVIII) which is vital for blood clot formation (O'Kelley et al, 2009). Haemophilia A is the result of a spontaneous gene mutation in FVIII, preventing the body from clotting normally. It is diagnosed by a combination of prolonged coagulation times together with a reduction in FVIII activities/concentrations (Dunning et al, 2009).

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canine
haemophilia A
factor VIII (FVIII)
Orpet & Jeffery's Ability Model (2007)