References

Aiken SW Principles of surgery for the cancer patient. Clin Tech Small Anim Pract. 2003; 18:75-91

Blackwood L, Murphy S, Buraco P European consensus document on mast cell tumours in dogs and cats. Vet Comp Oncol. 2012; 10:e1-29

Boudreaux B. Antimicrobial use in the veterinary cancer patient. Vet Clin North Am Small Anim Pract. 2014; 44:883-91

Bowles DB, Robson MC, Galloway PE, Walker L Owner's perception of carboplatin in conjunction with other palliative treatments for cancer therapy. J Small Anim Pract. 2010; 51:104-12

Brearley MJ, Hayes AM, Murphy S Hypofractionated radiation therapy for invasive thyroid carcinoma in dogs: a retrospective analysis of survival. J Small Anim Pract. 1999; 40:206-10

Bregazzi VS, Larue SM, Powers BE, Fettman MJ, Ogilvie GK, Withrow SJ Response of feline oral squamous cell carcinoma to palliative radiation therapy. Vet Radiol Ultras. 2001; 42:77-7

Charney SC, Bergman PJ, Mcknight JA Evaluation of intracavitary mitoxantrone and carboplatin for treatment of carcinomatosis, sarcomatosis and mesothelioma, with or without malignant effusions: a retrospective analysis of 12 cases (1997-2002). 2005; 3:171-81

Coomer A, Farese J, Milner R, Liptak J, Bacon N, Lurie D Radiation therapy for canine appendicular osteosarcoma. Vet and Comp Onc. 2009; 7:15-27

Doré M. Cyclooxygenase-2 expression in animal cancers. Vet Path. 2010; 48:254-65

Epstein M, Roden I, Griffenhagen G 2015 AAHA/AAFP pain management guidelines for dogs and cats. J Am Anim Hosp Assoc. 2015; 51:67-84

Fan TM. Pain management in veterinary patients with cancer. Vet Clin North Am Small Anim Pract. 2014; 44:989-1001

Farrelly J, McEntee MC Principles and applications of radiation therapy. Clin Tech Small Anim Pract. 2003; 18:82-7

Fox LE, Geoghegan SL, Davis LH, Hartzel JS, Kubilis P, Gruber LA Owner satisfaction with partial mandibuletomy or maxillectomy for treatment of oral tumours in 27 dogs. J Am Anim Hosp Assoc. 1997; 33:25-31

Hahn KA, Olgivie G, Rusk T Masitinib is safe and effective for the treatment of canine mast cell tumors. J Vet Int Med. 2008; 22:1301-9

Hayes A, Adams V, Scase T, Murphy S Survival of 54 cats with oral squamous cell carcinoma in United Kingdom general practice. J Small Anim Pract. 2007; 48:394-99

Hume KR, Johnson JL, Williams LE Adverse effects of concurrent carboplatin chemotherapy and radiation therapy in dogs. J Vet Int Med. 2009; 23:24-30

Klein MK. Multimodality therapy for head and neck cancer. Vet Clin North Am Small Anim Pract. 33:615-28

Kung MB, Poirier VJ, Dennis MM, Vail DM, Straw RC Hypofractionated radiation therapy for the treatment of microscopic canine soft tissue sarcoma. Vet Comp Oncol. 2014; https://doi.org/10.1111/vco.12121

Lana S, U'ren L, Plaza S, Elmslie R, Gustafson D, Morley P, Dow S Continuous low dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs. J Vet Int Med. 2007; 21:764-9

London CA, Malpas PB, Wood-Follis SL Multicenter, placebocontrolled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. Clin Can Res. 2009; 15:3856-65

London C, Mathie T, Stingle N Preliminary evidence for biologic activity of toceranib phosphate (Palladia®) in solid tumours. Vet Comp Oncol. 2012; 10:194-205

London CA, Gardner HL, Mathie T Impact of toceranib/piroxicam/cyclophosphamide maintenance therapy on outcome of dogs with appendicular osteosarcoma following amputation and carboplatin chemotherapy: a multi-institutional study. PloS One. 2015; 10

Marconato L, Romanelli G, Stefanello D Prognostic factors for dogs with mammary inflammatory carcinoma: 43 cases (2003-2008). J Am Vet Med Assoc. 2009; 23:967-72

Mason S. Palliative care in small animal oncology. In Pract. 2016; 38:203-17

Mathews K, Kronen PW, Lascelles D Guidelines for recognition, assessment and treatment of pain. J Small Anim Pract. 55:E10-E68

Mayer MN, Grier CK Palliative radiation therapy for canine osteosarcoma. Can Vet J. 2006; 47:707-9

Mellanby RJ, Herrtage ME, Dodson JM Owners' assessments of their dog's quality of life during palliative chemotherapy for lymphoma. J Small Anim Pract. 2003; 44:100-3

Mitchell L, Thamm DH, Biller BJ Clinical and immunomodulatory effects of toceranib combined with lowdose cyclophosphamide in dogs with cancer. J Vet Int Med. 2012; 26:355-62

Moore AS Radiation therapy for the treatment of tumours in small companion animals. Vet J. 2002; 164:176-87

Moore AS, Frimberger AE Oncology for veterinary technicians and nurses.Ames, Iowa: x: Wiley-Blackwell; 2010

Queiroga FL, Pires I, Lobo L, Lopes CS The role of Cox-2 expression in the prognosis of dogs with malignant mammary tumours. Res Vet Sci. 2010; 88:441-5

Tomlin JL, Sturgeon C, Pead MJ, Muir P Use of the bisphosphonate drug alendronate for palliative management of osteosarcoma in two dogs. Vet Rec. 2000; 147:129-32

Tripp CD, Fidell J, Anderson CL Tolerability of metronomic administration of lomustine in dogs with cancer. J Vet Int Med. 2011; 25:278-84

Tzannes S, Hammond MF, Murphy S, Sparkes A, Blackwood L Owners perception of their cats' quality of life during COP chemotherapy for lymphoma. J Feline Med Surg. 2008; 10:73-81

Approach to the companion animal cancer patient: current therapies

02 February 2017
16 mins read
Volume 8 · Issue 1

Abstract

As one of the most treatable of all the chronic diseases, a diagnosis of cancer ultimately leads to a discussion of treatment options, including therapy directed at the cancer as well as any associated pain or other clinical signs, including paraneoplastic disease, and any comorbidity. The goal of treatment is to achieve as good a quality of life as possible for as long as possible. Given that curative-intent definitive treatment is not always an option, palliative treatment is available and can make the animal comfortable during the latter part of life. The aim of this article is to describe the various cancer therapies available, focusing on the role the veterinary nurse can play in facilitating communication between owner and veterinary surgeon about treatment options and quality of life of the animal.

Veterinary oncology is a rapidly growing field with cancer being such a common diagnosis in small animal practice and owners increasingly willing to choose treatment for their pets. The goal of treatment is to achieve as good a quality of life as possible, for as long as possible, rather than to achieve a cure. With this goal in mind, outcomes can be good as diagnostic and treatment options continue to improve and become more widely available. Where definitive treatment is not an option, palliative treatment is available and can make the animal comfortable during the latter part of life. This is the second in a series of articles aimed to provide information for veterinary nurses (VN) involved in the care of companion animal cancer patients. The first article focused on the pre-treatment phase of care — diagnosis and staging. The aim of this article is to describe the various cancer therapies available, focusing on the role a VN can play in facilitating communication between owner and veterinary surgeon (VS) about treatment options and quality of life of the animal. It has been said that cancer is ‘the most treatable’ of all chronic diseases (Moore and Frimberger, 2010). During the past decade, there have been many advances in the treatment of cancer in pets. The traditional modalities (surgery, radiotherapy and chemotherapy) are still the mainstay of treatment although there are several new treatment modalities now becoming more commonly available and used in small animal practice.

Register now to continue reading

Thank you for visiting The Veterinary Nurse and reading some of our peer-reviewed content for veterinary professionals. To continue reading this article, please register today.