References

Böhm C, Schnyder M, Thamsborg SM Assessment of the combination of spinosad and milbemycin oxime in preventing the development of canine Angiostrongylus vasorum infections. Vet Parasitol. 2014; 199:(3-4)272-7 https://doi.org/10.1016/j.vetpar.2013.10.024

Böhm C, Petry G, Schmidt H, Raue K, Barthel F, Schaper R Evaluation of the persistent preventive efficacy of 2.5 % Moxidectin/10 % Imidacloprid spot-on (Advocate®, Advantage® Multi) in dogs experimentally infected with Angiostrongylus vasorum. Parasitol Res. 2017; 116:1-10 https://doi.org/10.1007/s00436-017-5487-x

Bourque A, Conboy G, Miller L, Whitney H, Ralhan S Angiostrongylus vasorum infection in 2 dogs from Newfoundland. The Can Vet J. 2002; 43:(11)876-9

Brennan SF, Mccarthy G, McAllister H, Bassett H, Jones BR Clinical signs, diagnosis and treatment of three dogs with angiostrongylosis in Ireland. Ir Vet J. 2004; 57:(2)103-9 https://doi.org/10.1186/2046-0481-57-2-103

Chapman PS, Boag AK, Guitian J, Boswood A Angiostrongylus vasorum infection in 23 dogs (1999–2002). J Small Anim Pract. 2004; 45:435-40

Colella V, Lia RP, Premont J Angiostrongylus vasorum in the eye: new case reports and a review of the literature. Parasit Vectors. 2016; 9 https://doi.org/10.1186/s13071-016-1440-6

Conboy G Natural infections of Crenosoma vulpis and Angiostrongylus vasorum in dogs in Atlantic Canada and their treatment with milbemycin oxime. Vet Rec. 2004; 155:(1)16-18

Conboy G Helminth parasites of the canine and feline respiratory tract. Vet Clin North Am Small Anim Pract. 2009; 39:(6)1109-26

Denk D, Matiasek K, Just FT Disseminated angiostrongylosis with fatal cerebral haemorrhages in two dogs in Germany: A clinical case study. Vet Parasitol. 2009; 160:(1-2)100-8 https://doi.org/10.1016/j.vetpar.2008.10.077

Elsheikha HM, Holmes SA, Wright I, Morgan ER, Lacher DW Recent advances in the epidemiology, clinical and diagnostic features, and control of canine cardio-pulmonary angiostrongylosis. Vet Res. 2014; 45 https://doi.org/10.1186/s13567-014-0092-9

Featherstone H, Scurrell E Ocular sampling in the dog and cat. In Practice. 2015; 37:510-39 https://doi.org/10.1136/inp.h5720

Koch J, Willesen JL Canine pulmonary angiostrongylosis: an update. Vet J. 2009; 179:(3)348-59 https://doi.org/10.1016/j.tvjl.2007.11.014

Lebon W, Tielemans E, Rehbein S Monthly administrations of milbemycin oxime plus afoxolaner chewable tablets to prevent Angiostrongylus vasorum infection in dogs. Parasit Vectors. 2016; 9:(1) https://doi.org/10.1186/s13071-016-1773-1

Maltman M, Wray J, Morgan E, Andrews D Angiostrongylosis clinical forum: a case presenting in a Terrier. Companion Animal. 2013; 18:315-21

Manning SP Ocular examination in the diagnosis of angiostrongylosis in dogs. Vet Rec. 2007; 160:625-7

Morgan ER1, Jefferies R, van Otterdijk L Angiostrongylus vasorum infection in dogs: Presentation and risk factors. Vet Parasitol. 2010; 173:(3-4)255-61 https://doi.org/10.1016/j.vetpar.2010.06.037

Negrin A, Cherubini GB, Steeves E Angiostrongylus vasorum causing meningitis and detection of parasite larvae in the cerebrospinal fluid of a pug dog. J Small Anim Pract. 2008; 49:(9)468-71 https://doi.org/10.1111/j.1748-5827.2008.00570.x

Penagos-Tabares F, Lange MK, Chaparro-Gutiérrez JJ, Taubert A, Hermosilla C Angiostrongylus vasorum and Aelurostrongylus abstrusus: Neglected and underestimated parasites in South America. Parasit Vectors. 2018; 11:(1) https://doi.org/10.1186/s13071-018-2765-0

Sasanelli M, Paradies P, Otranto D, Lia RP, de Caprariis D Haemothorax associated with Angiostrongylus vasorum infection in a dog. J Small Anim Pract. 2008; 49:(8)417-20 https://doi.org/10.1111/j.1748-5827.2008.00551.x

Schnyder M, Fahrion A, Ossent P Larvicidal effect of imidacloprid/moxidectin spot-on solution in dogs experimentally inoculated with Angiostrongylus vasorum. Vet Parasitol. 2009; 166:(3-4)326-32 https://doi.org/10.1016/j.vetpar.2009.09.004

Søland J, Bolt G Hypovolaemic shock after anthelmintic treatment of canine angiostrongylosis. J Small Anim Pract. 1996; 37:594-6

Wessmann A, Lu D, Lamb CR, Smyth B Brain and spinal cord haemorrhages associated with Angiostrongylus vasorum infection in four dogs. Vet Rec. 2006; 158:(25)858-63

Willesen JL, Kristensen AT, Jensen AL, Heine J, Koch J Efficacy and safety of imidacloprid/moxidectin spot-on solution and fenbendazole in the treatment of dogs naturally infected with Angiostrongylus vasorum (Baillet, 1866). Vet Parasitol. 2007; 147:(3-4)258-64

A heart-breaking disease: how to prevent lungworm infection

02 September 2018
9 mins read
Volume 9 · Issue 7

Abstract

Since first detected in the British Isles, in a Greyhound in Ireland in 1968, the lungworm Angiostrongylus vasorum has spread to become a prevalent parasitic disease, and a leading cause of morbidity and mortality, in dogs. Faced with the increasing threat posed by canine lungworm, parasitologists are tracing the geographic spread of infections; and some clinicians remain uncertain about the optimal frequency of dosing for preventive therapy. For this reason, control of canine lungworms has been an increasingly important focus of the veterinary profession, with significant progress being made on a number of fronts, particularly the diagnosis and treatment of lungworm disease. One notable success has been the development of potent anthelmintic drugs to control this disease. Despite this progress, infection due to A. vasorum remains a formidable clinical problem, and may continue to do so for many years to come. What has been learned over the past decade, is that control of lungworms is too complex to be handled by a single approach; and any attempt to do so may be unsuccessful. In this article, the author argues that the implementation of integrated parasite control strategies is crucial, in order to mitigate the risks caused by lungworms, reduce the transmission of infection and improve treatment outcomes.

Angiostrongylus vasorum is a nematode parasite that affects the cardiopulmonary system of canids (Elsheikha et al, 2014). It is maintained in a dog-slug-dog transmission cycle. There are many methods by which canine lungworm can be circulated in nature, creating more opportunities for dogs, and wild carnivores, to be exposed to the infective stages. Accidental ingestion of infected gastropods (snails or slugs) harboring infective third-stage larvae, is believed to be the main source of infection. Infection can also be transmitted through ingestion of an infected paratenic (transport) host. This gastropod-borne metastrongyloid parasite, has gained attention from the veterinary community due to its extensive distribution throughout the UK, mainland Europe, Asia and Africa. In the last few years, the number of cases of canine lungworm infection has risen in several regions of North America (Conboy, 2009), with increasing attention being paid to the epidemiology of this parasite in South America (Penagos-Tabares et al, 2018). A similar trend has been also observed in the UK (reviewed in Elsheikha et al, 2014).

Register now to continue reading

Thank you for visiting The Veterinary Nurse and reading some of our peer-reviewed content for veterinary professionals. To continue reading this article, please register today.